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BIG SUCCESS!!!!
HDF raises over $2 Million at the 40th birthday celebration
and tribute to its founder, Milton Wexler!!
Thursday, January 24, 2008
Casa del Mar
Santa Monica, CA
Click here for more information about the Benefit

FDA advisory committee votes unanimously to recommend approval of tetrabenazine for chorea associated with Huntington's disease.

This marks the first time in history that a drug could be approved in the U.S. to treat chorea associated with HD! Thank you all for your efforts and support!

IN MEMORY OF MILTON WEXLER


© Mariana Cook 1992

March 20, 2007

Dearest Friends and Family,

An unimaginable day has finally arrived.

Dr. Milton Wexler, a force of nature whose visionary presence changed hundreds of thousands of lives for the better, died Friday, March 16, 2007 of respiratory failure.

As he himself said, “I’ve had a very good ride through this life.”

Even though he died at age 98 and a half, he was as innovative, lucid, imaginative, creative and ahead of the curve as he was as a young man – he only got better with age! We want another century with him, at least – we miss him terribly.

In lieu of flowers, please send contributions to the Hereditary Disease Foundation, the organization Milton founded in 1968. For the past 40 years, he has been passionately devoted to finding cures for Huntington's disease and related disorders.

Donations made payable to the Hereditary Disease Foundation can be mailed to the Hereditary Disease Foundation, 3960 Broadway, 6th floor, New York, NY 10032. Contributions by credit card can be made online on the Hereditary Disease Foundation website – www.hdfoundation.org.

Affectionately,
Nancy and Alice Wexler

Click here to read Milton's obituaries.

 
Newsletter Now Available

Download the entire Summer 2007 newsletter as a PDF file now. Table of contents includes:

  • HDF Chairman Milton Wexler Tribute
  • HDF President Nancy Wexler Receives Franklin Institute Award
  • HDF Trustee Julie Andrews Helps Fight to Cure Huntington's Disease
  • 2007 HDF Workshop Updates
  • HDF Welcomes New Members of the Scientific Advisory Board
  • HDF Fundraising News
  • HDF Scientific Advisory Board News
  • 2007 HDF Science Funding
  • Your Legacy Today Advances the Science of Tomorrow

Hereditary Disease President Nancy Wexler to Receive Benjamin Franklin Medal in Life Science!
For 182 years, The Franklin Institute has honored the greatest men and women of science, engineering, and technology. The Franklin Institute Awards are among the oldest and most prestigious comprehensive science awards in the world.

Nancy Wexler featured in Monday, 4/23/07, Philadelphia Inquirer.

Among science's highest honors, The Franklin Institute Awards identify individuals whose great innovation has benefited humanity, advanced science, launched new fields of inquiry, and deepened our understanding of the universe.

HDF Leadership—President Nancy Wexler and Lifetime Director Julie Andrews featured in the March/April 2007 issue of Neurology Now magazine.

 
Breaking News

March 18, 2007 Sunday New York Times' front page article about one young woman's experience in testing positive for Huntington's disease "Confronting Life With a Lethal Gene," by Amy Harmon.

Hereditary Disease Foundation President Nancy Wexler is quoted in the beginning of the article.

 
Research News

Hereditary Disease Foundation Workshop Report Now Available!
January 20–21, 2007

Pipelines and Pathogenesis: New Horizons, Santa Monica, California.


Strategy to Find a Cure For Huntington’s Disease, Long-Supported by Hereditary Disease Foundation, Is Validated by Nobel Prize!
Congratulations to Andrew Z. Fire and Craig C. Mello,
Scientists Who Discovered RNA Interference
Awarded 2006 Nobel Prize in Physiology or Medicine!

In October, Fire and Mello were awarded the Nobel Prize for their discovery of an efficient and generalizable method for selectively turning off the expression of any gene in the nematode worm C. elegans. The method is known as RNA interference or RNAi. Fire and Mello published their groundbreaking discovery in the journal Nature in February of 1998. Since that time, RNAi has been shown to be an effective method for turning off the expression of genes in a wide variety of plant and animal species, including humans. The RNAi technique is now widely used in academic and industrial research laboratories to study the function of genes and plans are underway to develop RNAi-based treatments for a wide variety of diseases, including Huntington’s disease (HD).

Spurred by the excitement generated by Fire and Mello’s discovery, the Hereditary Disease Foundation began to organize, champion and support the development of gene-based therapy for HD and continues to be a leader in providing funding for RNAi research.


Hereditary Disease Foundation Symposium
August 10–14, 2006

HD 2006: Changes, Advances and Good News (CAG)n, Cambridge, Massachusetts.

Symposium Summary Report Now Available!
Scientists gathered to report promising innovative strategies and potential future therapies for Huntington’s disease and related disorders. Summary report, written by HDF's science writer, Marina Chicurel, Ph.D., now available.

Recent Science Funding Provided by the Hereditary Disease Foundation
Hereditary Disease Foundation grants, postdoctoral fellowships and research contracts are helping identify routes to the development of cures and treatments for Huntington’s disease and other similar hereditary disorders. With your support, the HDF’s Scientific Advisory Board, comprised of world-renowned experts in genetics, neurology, neuroscience, and therapy development, has funded groundbreaking research.

 
 
 

Praise for HDF

Everything I know about genomics I learned first at Hereditary Disease Foundation workshops!
Francis Collins, M.D., Ph.D.
Director, National Human Genome Research Institute
Recipient, Presidential Medal of Freedom, 2007
If one looks back in the development of human genetics in our current form, I think the Hereditary Disease Foundation played really the same role that the Rockefeller Foundation played in the 30s and 40s, when it permitted the development of molecular biology. It was a small group of people who weren't waiting around, but were giving money to the right people, with the thought that it was sensible.
November 1, 2005
Dr. James D. Watson, Chancellor
Cold Spring Harbor Laboratory
Winner of the Nobel Prize in Physiology or Medicine in 1962
Through the years, I have been blessed to work with superb and dedicated people, and I count the three of you, Milton, Nancy and Alice Wexler, to be at the top of that list.
Dr. Francis S. Collins, Director
National Human Genome Research Institute
National Institutes of Health
Through the active recruitment of new ideas, new technologies and new researchers, the Hereditary Disease Foundation has set the stage for important progress in our understanding of HD pathology. Their commitment to collaboration and community building within the HD field serves as a model for all scientific groups tackling human diseases.
Nature Medicine, October 2000
 

Funding News


HDF raises over $2 Million at the 40th birthday celebration and tribute to its founder, Milton Wexler!!
- Thursday, January 24, 2008
Casa del Mar, Santa Monica, CA

"Hoops for Hope," the annual Mike O'Brien Invitational basketball event, raises over $15,000 for the HDF!

 

In Memoriam

Milton Wexler
Alden "Buster" Blethen
G. William 'Bill' Fox

G. William "Bill" Fox

Don Fritts

Don Fritts

Vernon M. Ingram

Vernon M. Ingram

William 'Bill' Modell

William “Bill” Modell

Mike O'Brien

Mike O'Brien

Jack Penney

 
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